The evolution of human genome variation and population history. Tomas Marques-Bonet Profesor de Investigacion ICREA Instituto de Biologia Evolutiva Universidad Pompeu Fabra/CSIC Barcelona

Título: The evolution of human genome variation and population history

Ponente: Tomas Marques-Bonet, Profesor de Investigacion ICREA, Instituto de Biologia Evolutiva, Universidad Pompeu Fabra/CSIC, Barcelona

Resumen:

Despite great advances in sequencing technologies, we are just starting to understand population structure and recent adaptations of our recent history. Still, the phylogeny and adaptation of great apes, our closest living relatives, is still mainly unexplored. To explore this and other questions related to the evolution of human genomic variation we studied genome wide diversity patterns based on 79 great ape genomes covering almost all subspecies of great apes. The complete analyses of SNPs, Copy Number Variation and Epigenetic modifications has boosted our understanding on diversity, evolutionary genetics and demography to a fine-scale level that was not possible before. Overall, this project is one step forward to explain our diversity in an evolutionary context.